Products of conception (POC) are tissues that are created at conception that spontaneously miscarry. These tissues include chorionic villia, fetal membranes, or fetal tissue. Spontaneous miscarriages occur in 15% to 20% of all recognized human conceptions.

While there are many possible causes for a miscarriage, chromosomal anomalies can be identified in up to 50% of first-trimester miscarriages. As such, it is important to determine the possible chromosomal cause for the pregnancy loss